December 1992

Picture of the Month

Author Affiliations

From the Pediatric Dermatology Service, Massachusetts General Hospital, Boston.

Am J Dis Child. 1992;146(12):1473-1474. doi:10.1001/archpedi.1992.02160240083026

Denouement and Discussion 


Manifestations  Mastocytosis is a disorder characterized by the accumulation of an increased number of mast cells in the skin, and, sometimes, in other organs of the body. Systemic mastocytosis is more common in adults than in children. Three forms of this disorder occur in children: (1) solitary or few lesions known as mastocytomas (Fig 1); (2) generalized lesions (urticaria pigmentosa) (Fig 2); and (3) diffuse infiltration of the skin (diffuse cutaneous mastocytosis).A mastocytoma is a skin-colored to light brown nodule or plaque that is present at birth or develops in early infancy. The lesions may be found on any body

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