Sir.—Typically, the infant with meconium aspiration syndrome (MAS) is a term or postterm neonate with a birth weight exceeding 2500 g. In a series of 88 meconium-stained infants, Gregory et al1 found a mean birth weight of 2911 g and a mean gestation of 290 days or 10 days after the expected delivery date.1 After reviewing 125 cases of meconium-stained infants, Ting and Brady2 reported similar results.
In utero meconium passage occurs in only 3% of infants of gestational age younger than 36 weeks.3 In the past, meconium aspiration has been regarded entirely as a postnatal event. We report an unusual case of intrauterine meconium aspiration in a premature infant.
Patient Report.—A 610-g white male neonate was born to a 24-year-old gravida 2, para 0010 mother at 27 weeks' gestation by dates and examination. The pregnancy was complicated by maternal diethylstilbestrol exposure, hyperemesis, and
FALCIGLIA HS, KOSMETATOS N, BRADY K, WESSELER TA. Intrauterine Meconium Aspiration in an Extremely Premature Infant. Am J Dis Child. 1993;147(10):1035-1037. doi:10.1001/archpedi.1993.02160340021004