September 1995

Maternal-Fetal Toxicology: A Clinician's Guide

Author Affiliations

University of South Florida Tampa


2nd ed, edited by Gideon Koren, 824 pp, $175, ISBN 0-8247-8841-9, Marcel Dekker Inc, New York, NY, 1994.

Arch Pediatr Adolesc Med. 1995;149(9):1045. doi:10.1001/archpedi.1995.02170220111027

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Koren's experience in the mother-risk clinic in Toronto, Ontario, is designed to inform, counsel, and follow up women exposed to drugs, chemicals, or radiation during pregnancy. The comprehensive, up-to-date text is divided into four parts: "Drugs in Pregnancy," "Poisoning and Radiation in Pregnancy," "Genetic and Obstetric Considerations," and "Organization and Operation of Teratogen Information Services."

Particularly helpful is a 33-page table of maternal diseases and pregnancy outcome. A clever and unique feature is a brief clinical case summary at the beginning of most chapters and an answer to the question posed at the end; this enhances the clinical relevance of the book. A very timely topic covered in one chapter is periconceptual folate levels and neural tube defects. A listing of teratogen information services is very helpful. This text should not be compared with Shepherd's Catalog of Teratogenic Agents because this guide is not a catalogue and contains a host

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