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June 1996

An Unusual Presentation of Erythema Toxicum Scrotal Pustules Present at Birth

Author Affiliations

Children's Hospital of Pittsburgh 3705 Fifth Ave at DeSoto Street Pittsburgh, PA 15213

Arch Pediatr Adolesc Med. 1996;150(6):649-650. doi:10.1001/archpedi.1996.02170310083017

Erythema toxicum neonatorum is the most common dermatological condition of the newborn period with an incidence of 30% to 70%.1-3 Metlinger described the rash as early as the 15th century.4 It is a benign eruption with a variable presentation that has been reported to occur at lower incidence with diminishing gestational age and birth weight.5 The precise cause of the rash is unknown; however, proposals range from an allergic phenomenon to mechanical or chemical irritation.2,6 The rash may be present at birth7 but more commonly appears on day of life 2 to 4.8 It consists of pale yellow to white papules or pustules on an irregular erythematous base; it has been described as having a "flea-bitten appearance."9 Lesions can be found on any part of the body, although palms and soles are usually spared. There are no systemic findings except blood eosinophilia; counts

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