November 1996

Catch-up Growth During Childhood Among Very Low-Birth-Weight Children

Author Affiliations

From the Departments of Pediatrics (Dr Hack) and Epidemiology and Biostatistics (Dr Borawski-Clark), Case Western Reserve University, Cleveland, Ohio; and the Department of Pediatrics, Emory University, Atlanta, Ga (Dr Weissman).

Arch Pediatr Adolesc Med. 1996;150(11):1122-1129. doi:10.1001/archpedi.1996.02170360012002

Objectives:  To examine growth attainment and correlates of catch-up growth at 8 years of age in a cohort of very low-birth-weight (VLBW) children (<1500 g), including appropriate and small-for-gestational-age children, and to compare their growth with normal-birth-weight (NBW) children.

Design:  Eight-year longitudinal follow-up of a cohort of VLBW children. A geographically based, randomly selected sample of NBW children was recruited at 8 years of age.

Setting:  Tertiary perinatal center.

Participants:  Two hundred forty-nine VLBW children born between January 1,1977, and December 31, 1979 (78% of survivors), of whom 199 were born appropriate for gestational age and 50 were small for gestational age (<−2 SD). The NBW population included 363 children.

Main Outcome Measures:  For the VLBW population, rates of subnormal weight (below the third percentile) and height were obtained at birth, at 40 weeks (term), and at 8 and 20 months. For the VLBW and NBW populations, mean weight, height, and percentile distribution at 8 years were derived from the National Center for Health Statistics standards.

Results:  Catch-up growth to above the third percentile occurred between 40 weeks and 8 months, 8 and 20 months, and up to 8 years of age among the VLBW children. At 40 weeks, 54% were subnormal in weight and 60% were subnormal in height; at 8 months, 33% and 22%, respectively, and at 8 years, 8% were subnormal in weight and height. Small-for-gestational-age children had lower rates of catch-up growth. Multivariate analyses disclosed maternal height, race, birth weight, and neurologic abnormality to predict percentile distribution of height; and maternal height, small for gestational age, and neurologic abnormality to predict subnormal height.

Conclusions:  Catch-up growth occurs during child-hood among VLBW children. These results have implications when counseling parents about the potential growth attainment of their children.Arch Pediatr Adolesc Med. 1996;150:1122-1129