[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.161.241.199. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
August 1997

Thrombocytosis in Sickle Cell Anemia-Reply

Author Affiliations

University of Pittsburgh Medical Center 100 Lothrop St Pittsburgh, PA 15213-2582

Arch Pediatr Adolesc Med. 1997;151(8):859. doi:10.1001/archpedi.1997.02170450109023

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

Our patient has been followed up at Children's Hospital of Pittsburgh, Pittsburgh, Pa. He had several episodes of reactive thrombocytosis. The original bone marrow aspirates and biopsy specimens were performed to exclude a myelodysplasia. A mild increase of reticulin in the bone marrow biopsy specimen is a common finding in hypercellular marrows. The increase in megakaryocytes was interpreted as reactive, because it was associated with thrombocytosis. Thrombocytosis is not the usual finding associated with myelofibrosis, but it can be associated with acute megakaryocytic leukemia or essential thrombocythemia demonstrated or resulted in a normal karyotype. Even though we considered the possibility of a myelodysplastic process, none of our studies or the clinical course of this patient has so far supported that diagnosis.

First Page Preview View Large
First page PDF preview
First page PDF preview
×