In a cluster-randomized trial evaluating the impact of an after-school soccer and youth development program on students' physical activity, and weight status, Madsen et al found that the program increased moderate-to-vigorous physical activity among overweight and obese children.
Schreier et al tested a novel intervention that assigned adolescents to volunteer with elementary school–aged children, finding that the intervention successfully changed risk markers for cardiovascular disease.
In a 24-month postbaseline survey conducted 6 months after Prime Time, a youth development intervention designed to reduce pregnancy risk among adolescent girls, Sieving et al found that the intervention group reported significantly more consistent use of condoms, hormonal contraception, and dual-method contraception than the control group.
Bauer et al examined the effect of intimate partner violence (IPV) and parental depressive symptoms during the first 3 years of a child's life. Exposure to both IPV and depression before age 3 years was associated with preschool-aged onset of attention-deficit/hyperactivity disorder.
Liu et al examined the brain morphologic features and associated impulsive behaviors in adolescents following prenatal exposure to cocaine and/or tobacco, finding that such exposure can differentially affect brain maturation and underlie enhanced susceptibility to impulsivity.
In a 3-month randomized multicenter clinical trial followed by a 3-month open-label extension,
Kelly et al evaluated the effects of exenatide on body mass index and cardiometabolic risk factors in adolescents with severe obesity. The results provided preliminary evidence supporting glucagon-like peptide-1 receptor agonist therapy.
Magge et al conducted a retrospective study to understand the role of zinc protoporphyrin (ZPP) in iron deficiency screening in a low-income pediatric population. The results suggested that ZPP may be appropriate for such screening.
Mullane et al tested whether reduced lung function in early life was associated with increased risk for persistent wheeze at age 18 years. Wheeze at age 18 was associated with active smoking, but only among those with reduced lung function in infancy.
Douglas-Escobar et al reviewed the intestinal microbiome, with a focus on new studies showing there is an important link between the microbes that inhabit the intestinal tract and the developing brain. An understanding of this link may help treat various neurobehavioral problems.
Rachelefsky and Farrar reviewed the application of a control model based on impairment and risk in pharmacotherapy for children with allergic rhinitis. Treatment of allergic rhinitis improved disease control in children by reducing disease-associated impairment and risk.
In This Issue of JAMA Pediatrics. JAMA Pediatr. 2013;167(4):316. doi:10.1001/jamapediatrics.2013.61