THE INFANT pictured in Figure 1 was a 415-g female born at 22 weeks' gestational age to a 17-year-old gravida 2, para 1 mother. The mother's previous pregnancy produced a healthy child. This pregnancy was complicated by a foul-smelling vaginal discharge and abdominal cramps 2 days prior to admission to the hospital. At admission she had a high leukocyte count and fever. After amniocentesis, she was delivered of this female infant, who lived for 8 hours. The placenta weighed 193 g and had necrotizing acute chorioamnionitis (Figure 2 and Figure 3). All 3 umbilical vessels had vasculitis and funisitis. Airspaces were filled with polymorphonuclear leukocytes (Figure 4). Amniotic fluid and postmortem cultures grew Haemophilus influenzae biotype 1.
Pinar H, Sotomayor E, Singer DB. Pathological Case of the Month. Arch Pediatr Adolesc Med. 1998;152(2):199-200. doi:10.1001/archpedi.152.2.199