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This Month in Archives of Pediatrics and Adolescent Medicine
October 2002

This Month in Archives of Pediatrics & Adolescent Medicine

Arch Pediatr Adolesc Med. 2002;156(10):965. doi:10.1001/archpedi.156.10.965
The Efficacy of Duct Tape vs Cryotherapy in the Treatment of Verruca Vulgaris (the Common Wart)

Warts are a very common pediatric issue, for which a wide variety of treatments have been tried. In this randomized controlled trial, Focht and colleagues compared standard cryotherapy with the use of duct tape, changed once per week for 2 months. Warts resolved in 85% of the patients treated with duct tape, compared with 60% of those treated with freezing (P<.05). The majority of warts responded within the first month of treatment, and the treatment was well accepted by parents and children.

Economic Analyses of Respiratory Syncytial Virus Immunoprophylaxis in High-Risk Infants: A Systematic Review

Respiratory syncytial virus (RSV) infection is associated with high morbidity and costs estimated at $342 million annually. Immunoprophylaxis against RSV has been developed and recommended for high-risk infants, but it is expensive. Kamal-Bahl and colleagues conducted a systematic review of economic analyses of RSV immunoprophylaxis. They found that estimates from 12 prior studies ranged from cost savings to considerable incremental costs per hospitalization avoided. Studies with some form of industry funding were more likely to report the possibility of cost savings of prophylaxis in the entire high-risk population than studies without industry funding (100% vs 0%, respectively).

A Randomized Placebo-Controlled Trial of Mebendazole for Halitosis

Based on an anecdotal experience brought to their attention by a patient's mother, investigators in Turkey conducted a randomized controlled trial of treatment with mebendazole in children with chronic halitosis. Approximately a third of each group had parasites isolated from their stools. Of the children with parasitic infection, halitosis had resolved in 64% of those treated with mebendazole, compared with 8% of those treated with placebo. There was no significant difference in resolution of halitosis in those without parasitic infection.

Consequences and Correlates of Adolescent Depression

An analysis of the 1997 Commonwealth Fund Survey of 4684 students between 10 and 18 years of age revealed that 9% of girls and 5% of boys were found to be depressed. Rates of depression were 4-fold higher among girls and boys from low-income families compared with those from high-income families. Depression was associated with missing 1 day or more of school per month, and with smoking, binge drinking, and suicidal ideation. The study emphasizes the need for routine screening for appropriate treatment of adolescents with depression.

Randomized Trial to Prevent Sensitization to Mite Allergens in Toddlers and Preschoolers by Allergen Reduction and Education: One-Year Results

The best single predictor of asthma in children in developed countries is allergic sensitization to dust mite allergens. A randomized controlled trail was conducted in Germany, Greece, Lithuania, and England to prevent the sensitization to dust mite allergens in 566 high-risk toddlers and preschoolers. The environmental intervention in the child's home, combined with education, reduced dust mite sensitization by half at the 1-year follow-up examination (3.0% vs 6.5%). Simple, inexpensive measures can be effective in reducing sensitization and the potential onset of asthma in high-risk children.