To evaluate the role of intracranial pressure in the production of retinal hemorrhage in young children, Shiau and Levin reviewed of published clinical, postmortem, and experimental research findings worldwide pertinent to their review objective. They used PubMed, MEDLINE, and Ovid Evidence-Based Medicine Reviews as well as references found in other published articles to conduct searches.
Wilkinson et al review recently published data that cast doubt on the analgesic properties of sucrose in newborn infants and analyze the philosophical and ethical questions that they raise. An editorial by Schechter provides commentary.
Sonneville et al determine whether calcium, vitamin D, and/or dairy intakes are prospectively associated with stress fracture risk among female adolescents.
In a prospective 18-month trial, Gabbay and colleagues evaluated the effect of cholecalciferol on peripheral cytokine/chemokine levels, regulatory T cells, and residual β-cell function decrease when given as adjunctive therapy to insulin in 38 patients with new-onset type 1 diabetes mellitus.
In a randomized, double-blind pilot trial, the Finnish Dietary Intervention Trial for the Prevention of Type 1 Diabetes, Vaarala and coauthors test whether weaning to a bovine insulin–free cow’s milk formula reduces type 1 diabetes mellitus–associated autoantibodies in children at genetic risk.
In a prospective, longitudinal cohort study, Yeates et al examine reliable change in postconcussive symptoms and its functional consequences among children with mild traumatic brain injury over the first year postinjury as compared with children with orthopedic injuries.
Cheong et al hypothesized that whole-body hypothermia treatment for neonatal hypoxic-ischemic encephalopathy (HIE) would reduce significant cerebral lesions characteristic of HIE on magnetic resonance imaging (MRI), that MRI would be prognostic of death or major disability at 2 years of age, and that the prognostic utility of MRI would not be altered by hypothermia treatment.
In children with traumatic brain injury, Bennett and coauthors conducted a retrospective chort study to describe between-hospital and patient-level variations in intracranial pressure monitoring and to evaluate intracranial pressure monitoring in association with hospital features and outcome.
Ali uses a case-control study design to determine whether Helicobacter pylori is associated with infantile colic.
Rodgers and Topping evaluate the effectiveness of the requirements of the voluntary safety standard for drawstrings on children’s upper outerwear garments in preventing child deaths resulting from drawstring entanglement.