Tamma et al determined whether definitive combination antibiotic therapy affects mortality and nephrotoxicity in pediatric patients with gram-negative bacteremia.
Barnhart et al performed a retrospective, observational cohort study to compare the effect of fundoplication at the time of gastrostomy tube (GT) placement vs GT placement alone on subsequent reflux-related hospitalizations in 4163 infants with neurological impairment born between 2005 and 2010 at 42 US children’s hospitals.
Yamakawa et al examine the associations of breastfeeding with overweight and obesity among schoolchildren in Japan, with adjustment for the potential confounders.
Momper et al compared US Food and Drug Administration–approved adult and adolescent drug dosing and assessed the utility of allometric scaling for the prediction of drug clearance in the adolescent population.
Narad and colleagues investigated the combined risks of adolescence, attention-deficit/hyperactivity disorder (ADHD), and distracted driving (cell phone conversation and text messaging) on driving performance. Winston and colleagues provide a related editorial.
Schwartz et al further validate the Social-ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) via feedback from stakeholders (patients, parents, and providers) from a medically diverse population in need of life-long follow-up care, survivors of childhood cancer.
Grønborg et al estimate the relative recurrence risk for ASDs in a Danish population, including recurrence in full- and half-siblings, and examine time trends in ASDs relative to the recurrence risk. They determine the adjusted HR for ASDs among children having an older sibling with ASDs compared with children not having an older sibling with ASDs.
Sanderson et al identify clinician attitudes regarding the meaning, implication, and timing of the do-not-resuscitate order for pediatric patients. See the editorial by Lantos.
Gregory and colleagues examined whether induced (stimulating uterine contractions prior to the onset of spontaneous labor) and/or augmented (increasing the strength, duration, or frequency of uterine contractions with spontaneous onset of labor) births are associated with increased odds of autism.
Moore et al performed a meta-analysis of the 4- to 8-year neurodevelopmental outcomes of extremely premature infants to determine the rate of moderate to severe and severe neurodevelopmental impairment by gestational age and the difference in impairment rates between the successive weeks of gestation. See the Editorial by Belfort.