Douglas-Escobar and coauthors provide a brief review of the intestinal microbiome, with a focus on new studies showing that there is an important link
between the microbes that inhabit the intestinal tract and the developing brain.
Rachelefsky and Farrar review the application of a control model based on impairment and risk in pharmacotherapy for children with allergic rhinitis.
Madsen and colleagues conducted a cluster-randomized trial to evaluate the impact of a community-based after-school soccer and youth development program, America SCORES, on students' physical activity, weight status, and fitness.
Schreier et al test a novel intervention that assigned adolescents to volunteer with elementary
school-aged children as a means of improving adolescents' cardiovascular risk profiles.
Sieving et al evaluated sexual risk behaviors and related outcomes with a 24-month postbaseline survey conducted 6 months after the conclusion of the Prime
Time youth development intervention, designed to reduce pregnancy risk among adolescent girls.
Bauer et al examine the association between parent reports of intimate partner violence (IPV) and depressive symptoms within the first 3 years of a child's life
with subsequent mental health conditions and psychotropic drug treatment.
Liu and colleagues examined the brain morphologic features and associated impulsive behaviors in adolescents following prenatal exposure to cocaine and/or tobacco. Nora D. Volkow, MD, provides a related editorial.
In a 3-month, randomized, double-blind, placebo-controlled, multicenter clinical trial followed by a 3-month open-label extension, Kelly and coauthors evaluate the
effects of exenatide on body mass index and cardiometabolic risk factors in adolescents with severe obesity. See the editorial by Schwimmer.
Magge and colleagues conducted a retrospective longitudinal study of data from electronic medical records to understand the role of zinc protoporphyrin in iron
deficiency screening in a low-income pediatric population, as well as to describe the prevalence and trends of abnormal ZPP and the response to iron therapy. Robert D. Baker, MD, PhD, provides a related editorial.
Mullane et al test the hypothesis that reduced lung function in early life is associated with increased risk for persistent wheeze at age 18 years. See the
editorial by Carlsen.