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Letters to the Editor
January 2013

Inappropriate Data and Measures Lead to Questionable Conclusions

Author Affiliations

Author Affiliations: Department of Psychology, Metropolitan State University, St Paul, Minnesota (Dr Spielmans); Discipline of Psychiatry, Adelaide University, Adelaide, South Australia (Dr Jureidini), and Discipline of Psychiatry, University of Queensland, St Lucia, Queensland (Dr Purssey), Australia; and Department of Psychological Medicine, Cardiff University, Hergest Unit, Bangor, Wales (Dr Healy).

JAMA Psychiatry. 2013;70(1):121-123. doi:10.1001/jamapsychiatry.2013.747

In recent articles, Gibbons and colleagues1,2 concluded that antidepressants lowered suicidality relative to placebo among adult patients while demonstrating no difference in suicidality among youths; they further concluded that antidepressants possessed robust efficacy vs placebo. However, there are several problems with the underlying data and their choice of suicidality measures.

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