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Comment & Response
May 2014

Dose Reduction/Discontinuation for First-Episode Psychosis

Author Affiliations
  • 1Mental Health Services North–Holland North, the Netherlands

Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Psychiatry. 2014;71(5):585. doi:10.1001/jamapsychiatry.2013.4655

To the Editor We congratulate Wunderink et al1 for their long-term follow up of 7 years of patients with remitted first-episode psychosis. Their results suggest superior rates of social functioning for patients who receive dose reduction/discontinuation compared with maintenance treatment, despite a higher relapse rate during the first 3 years of treatment in the dose reduction/discontinuation group.

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