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April 2000

Exploring the Neurofunctional Organization of Face Processing in Autism

Arch Gen Psychiatry. 2000;57(4):344-346. doi:10.1001/archpsyc.57.4.344

SOCIAL dysfunction in autism is severe and likely involves abnormalities in multiple neural regions. One important constituent of social interchanges is processing of information provided by the face.

Neural systems that normally mediate face processing have been vigorously investigated15 and results from neuroimaging studies of normal subjects provide robust evidence that face processing involves increased activation of the fusiform gyrus (FG). The noted consistency across normal individuals and different paradigms is such that some scientists claim that the FG is selective for faces.6

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