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In their letter, Perna et al present data on the relationship in children
between respiration and anxiety. Children of parents with panic disorder were
shown to exhibit irregularities in respiration relative to children of psychiatrically
healthy parents, even when children with anxiety disorders are excluded. This
suggests that a study of respiration might illuminate developmental theories
of panic disorder. Such efforts to replicate and extend findings from our
study raise interesting questions.
Pine DS. Respiration in Children at Risk for Panic Disorder. Arch Gen Psychiatry. 2002;59(2):186. doi: