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Letters to the Editor
March 2002

D-Lactate and the False Suffocation Alarm

Arch Gen Psychiatry. 2002;59(3):287. doi:10.1001/archpsyc.59.3.287

The false suffocation alarm hypothesis was proposed by Klein1 in light of his and his colleagues' earlier finding that D-lactate infusion was almost as effective as L-lactate in inducing panic attacks.2 This hypothesis has now become widely accepted, but in our view, it is fundamentally flawed.

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