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Research Letter
December 2015

Dose-Response Association Between Psychological Distress and Risk of Completed Suicide in the General Population

Author Affiliations
  • 1Research Department of Epidemiology and Public Health, University College London, London, England
  • 2Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, Scotland
  • 3Charles Perkins Centre, University of Sydney, Sydney, New South Wales, Australia

Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Psychiatry. 2015;72(12):1254-1256. doi:10.1001/jamapsychiatry.2015.2107

Elevated suicide rates in people with clinical depression, as indexed by hospitalizations or use of psychiatric outpatient services, are well documented.1 However, the association between depression across the full range of severity and subsequent suicide risk is unknown. With single-cohort studies insufficiently powered to examine this relation, to our knowledge, we provide the first pooling of individual-level data from a series of large general population–based cohort studies.

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