In Reply In our publication in JAMA Psychiatry,1 we reported that the structure of symptom networks is related to the course of depression. Our findings are based on a between-patients design. Although we agree with Bos and Wanders that this has implications for the interpretation of our results, we do not think their conclusions are warranted.
van Borkulo CD, Borsboom D, Schoevers RA. Group-Level Symptom Networks in Depression—Reply. JAMA Psychiatry. 2016;73(4):411-412. doi:10.1001/jamapsychiatry.2015.3157