In Reply We agree with Begemann and colleagues on the importance of considering relevant environmental factors in studies investigating the association between psychotic experiences and cognition. An association between childhood trauma and risk for later psychosis has been documented.1 Indeed, we found strong evidence in the South East London Community Health (SELCoH) Study for higher rates of psychotic experiences in those who were physically or sexually abused during childhood.2 While it remains unclear whether the association between childhood trauma and risk for psychosis is a causal one, plausible psychological and biological mechanisms have been proposed1 and future work, particularly using longitudinal designs, may shed further light on this important question.
Mollon J, Morgan C, Reichenberg A. Childhood Trauma as a Neglected Factor in Psychotic Experiences and Cognitive Functioning—Reply. JAMA Psychiatry. 2016;73(8):876-877. doi:10.1001/jamapsychiatry.2016.1170