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Research Letter
November 2016

Association Between Levels of High-Sensitivity C-Reactive Protein and General Psychological Distress Symptoms

Author Affiliations
  • 1Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
  • 2Department of Health Promotion Center, Samsung Medical Center, Seoul, Korea
  • 3Pacific Behavioral Research Foundation, Carmel, California
JAMA Psychiatry. 2016;73(11):1199-1201. doi:10.1001/jamapsychiatry.2016.2167

The inflammatory marker high-sensitivity C-reactive protein (hs-CRP) is associated with symptoms of depression.13 A recent study reported that elevated levels of hs-CRP in the general population are associated with specific depressive symptoms of low energy, sleep disturbance, and appetite disturbance3; however, common general psychological distress symptoms (GPDS) were not investigated. We tested the association between levels of hs-CRP and GPDS in the general population.

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