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Research Letter
November 16, 2016

Distinct Relationships Between Visual and Auditory Perceptual Abnormalities and Conversion to Psychosis in a Clinical High-Risk Population

Author Affiliations
  • 1New York State Psychiatric Institute, Department of Psychiatry, Columbia University, New York
JAMA Psychiatry. Published online November 16, 2016. doi:10.1001/jamapsychiatry.2016.3055

Hallucinations are a ubiquitous symptom experienced across psychotic disorders. This symptom, particularly in its auditory form, is widely thought to share a common substrate with other positive symptoms.1 However, only unusual thought content and thought disorganization, not perceptual abnormalities (eg, hyperacusis, illusions, and momentary hallucinations), are associated with conversion to psychosis in clinical high-risk (CHR) populations,2,3 despite the high incidence of perceptual abnormalities.2

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