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Letters to the Editor
November 2000

Treatment of Atypical Depression With Cognitive Therapy or Phenelzine

Arch Gen Psychiatry. 2000;57(11):1084. doi:10.1001/archpsyc.57.11.1084

The syndrome of atypical depression is often characterized by a particularly chronic, recurrent course.1 It is interesting to speculate whether cognitions related to interpersonal rejection sensitivity, in addition to primary depressogenic cognitions, contribute to this chronicity. The finding of Jarrett et al2 that cognitive-behavioral therapy is an effective acute treatment for atypical depression is thus of great theoretical and practical interest. The 24-month follow-up should shed further light on potential long-term benefits of cognitive-behavioral therapy for this often refractory population.

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