Comparative treatment studies in children with attention-deficit/hyperactivity disorder (ADHD) are critical not only to clinical knowledge, but also to the controversy about medication. Therefore, the Multimodal Treatment Study of Children With ADHD (MTA)1,2 represents a major contribution. During 14 months, children with ADHD symptoms improved as much when using medication alone as when using medication combined with an ambitious psychosocial treatment, and both were superior to psychosocial treatment alone, which was indistinguishable from treatment in the community.
Klein RG. MTA Findings Fail to Consider Methodological Issues. Arch Gen Psychiatry. 2001;58(12):1184-1185. doi: