We appreciate the opportunity to reply to several letters to the editor concerning the Multimodal Treatment Study of Children with attention-deficit/hyperactivity disorder (ADHD) (MTA).1,2 These letters nicely illustrate some of the controversies and differences of opinion concerning ADHD, its diagnosis, and treatments. Herein, we respond to the points raised by these letters and summarize the thinking that led to what we think is a balanced interpretation informed by a thorough knowledge of the design, limitations, and strengths of the study.
Jensen PS, The MTA Cooperative Group. MTA Findings Fail to Consider Methodological Issues—Reply. Arch Gen Psychiatry. 2001;58(12):1185-1187. doi: