We thank Dr Antonuccio for his comments on the TADS. Dr Antonuccio makes the point that the TADS treatments eventually converge and that medications come with greater risks than CBT at all points. On this basis, he argues that CBT alone may represent the best balance of benefit and risk, with combined treatment (COMB) a distant second choice if speed of response is a major consideration. While there is wisdom in what he says, the data and clinical realities tell a somewhat more subtle and complex story.
March JS, TADS Team. Tailoring Treatment to Parental Values: A Comment on TADS—Reply. Arch Gen Psychiatry. 2008;65(6):723-724. doi:10.1001/archpsyc.65.6.723-b