[Skip to Content]
[Skip to Content Landing]
Citations 0
Letters to the Editor
August 2009

Heart Rate Variability and Depression: Sleep-Related Breathing Disorders as Confounder?

Arch Gen Psychiatry. 2009;66(8):915-917. doi:10.1001/archgenpsychiatry.2009.102

Licht et al1 discuss a relationship between depression and heart rate variability in their sample, which was also studied for the presence of other health-related variables, including heart disease and chronic medical conditions. Not specifically mentioned in their report is the presence of sleep-related breathing disorders (including sleep apnea) as a potential confounder, which is surprising given the evidence that exists linking these conditions to both diminished heart rate variability2 and depression.3

First Page Preview View Large
First page PDF preview
First page PDF preview