The purpose of this study is to investigate the covariation of certain psychiatric. psychological, physiological, and biochemical variables with improvement in psychiatric patients treated with real or simulated electroconvulsive therapy. An earlier report focused on the therapeutic effectiveness of certain components of the treatment process (i. e., electricity, convulsion, unconsciousness).3 Results indicated that the experimental variations of actual or simulated electroshock did not differ in the therapeutic effectiveness to an extent greater than chance. The present report is, therefore, concerned not with the electroshock variable but with (a) the prediction of improvement and (b) the further understanding of the concomitants of improvement.
BRILL NQ, CRUMPTON E, EIDUSON S, GRAYSON HM, HELLMAN LI. Predictive and Concomitant Variables Related to Improvement with Actual and Simulated ECT. AMA Arch Gen Psychiatry. 1959;1(3):263-272. doi:10.1001/archpsyc.1959.03590030047005