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While attracting a small and rather vocal core of followers, CO2 therapy is not extensively used in the treatment of the behavior disorders, even by those whose therapeutic approach to problems of mental illness is essentially pharmacologically and somatically oriented. The results of this investigation are not likely to win over new adherents, for with regard to fundamental parameters of change, CO2 therapy was found to be wanting.
This book is an essentially descriptive report of a research project spanning many years, employing thousands of statistical analyses (the book jacket states that over 10,000 in all were performed) and utilizing considerable manpower, which evaluates the efficacy of CO2 therapy. It does not attempt to answer questions of a theoretical nature concerning the presumed effects of CO2, that is its mode of physiological or neural action. Rather, the focus is on the empirical considerations of whether disturbed patients are benefited and
Rothstein R. Carbon Dioxide Therapy.. Arch Gen Psychiatry. 1962;7(2):151-153. doi:10.1001/archpsyc.1962.01720020075018