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Article
May 1965

Psychophysiology of Monozygotic Male Twins

Author Affiliations

BOSTON
From the Medical Clinics, Peter Bent Brigham Hospital and the Department of Psychiatry, Harvard Medical School. Associate Clinical Professor of Psychiatry, Harvard Medical School and Physician, Peter Bent Brigham Hospital (Dr. Fox); Assistant Clinical Professor of Psychiatry, Harvard Medical School and Senior Associate in Psychiatry, Peter Bent Brigham Hospital (Dr. Gifford); Clinical Associate in Psychiatry, Harvard Medical School and Associate in Psychiatry, Peter Bent Brigham Hospital (Dr. Valenstein); and Associate in Psychology, Department of Psychiatry, Harvard Medical School and Associate Staff-Medicine (Psychiatry), Peter Bent Brigham Hospital (Dr. Murawski).
William J. Reddy, ScD, supervised the biochemical determinations.

Arch Gen Psychiatry. 1965;12(5):490-500. doi:10.1001/archpsyc.1965.01720350058008
Abstract

THE SPECIAL psychology of the individuals who comprise a pair of identical twins has recently attracted considerable interest.1-7 Difficulties in their establishment of a sense of individual identity as well as unusual patterns of alliance and aggressive competition have shed light on certain aspects of developmental psychology and character formation in nontwins.

Our observations of twins were part of a larger study8 of supposedly healthy males most of whom were recruited as research subjects from neighboring colleges where they were students. The aim of the project was to correlate personality structure with relatively constant homeostatic patterns during phases of everyday life experience as measured by certain endocrine and exocrine indices of hypothalamic response. We have focused on the urinary excretion of 17-hydroxycorticosteroids (17OHCS), measured by the method of Reddy et al,9 and 17-ketosteroids (17-KS), determined by a modification of

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