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March 1966

Inhalation Psychosis and Related StatesA Review

Author Affiliations

From the USPHS Hospital, Lexington, Ky.

Arch Gen Psychiatry. 1966;14(3):315-322. doi:10.1001/archpsyc.1966.01730090091014

IT HAS LONG been known that affect and cognition may be considerably influenced by the inhalation of various substances. Both natural and artificial perfumes are prized for this very reason. Recently, however, attention has been drawn in both the professional and the popular press to persons who have become frankly psychotic while inhaling such substances as gasoline and model airplane glue. Because of the general concern in various quarters about these phenomena, a review of what has been learned appears to be indicated. It is quite possible that the further study and understanding of the states produced by the inhalation of such substances may reveal more differences than similarities, but in the present state of our knowledge it is more convenient to consider them together. In this discussion the pathological end point of these practices will be referred to as inhalation psychosis, and clinical syndromes due

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