By J. B. Chassan. Price, $5.75. Pp 280. Appleton-Century-Crofts, 440 Park Ave, S, New York 10016, 1967.
This book has already been reviewed in the Archives of General Psychiatry,1 the previous reviewer having been more favorably impressed by it than I was. Chassan has much to say that might be useful in clinical psychiatric research, but also much which is misleading and wrong.
The first four chapters are excellent. Chapter 1 surveys the logical and probabilistic foundations of statistical inference; chapter 2 presents some of the simpler and more commonly applied statistical techniques; chapter 3 explains the need for randomization and for adequate control groups; and
chapter 4 describes the rationale for, the execution of, and the pitfalls in the doubleblind clinical trial. In the latter chapter Chassan in effect says, and I agree with him, that unless a clinical team is prepared to put up with the scientific rigor and personal sacrifice demanded by double-blind trials, it should not even attempt such a study. The
Fleiss JL. Research Design in Clinical Psychology and Psychiatry.. Arch Gen Psychiatry. 1968;19(3):378-380. doi:10.1001/archpsyc.1968.01740090122015