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February 1971

The Hyperactive Child SyndromeNormal Chromosome Findings

Author Affiliations

St. Louis
From the Division of Medical Genetics, departments of pediatrics and medicine (Drs. Warren and Sly and Mr. Karduck), and the Department of Psychiatry (Drs. Bussaratid and Stewart), Washington University School of Medicine, and St. Louis Children's Hospital, St. Louis. Dr. Warren is currently at the Mailman Center for Child Development, Miami, Fla.

Arch Gen Psychiatry. 1971;24(2):161-162. doi:10.1001/archpsyc.1971.01750080065009

Nuclear sex determinations were done on 96 patients (82 boys and 14 girls) under psychiatric care for the hyperactive child syndrome. Complete karyotype analysis was donc on lymphocytes from peripheral blood of 23 of these patients (20 boys and 3 girls). No evidence of sex chromosome aneuploidy or of other chromosome abnormality was found. It was concluded that a recognizable chromosome abnormality is not a major cause of the hyperactive child syndrome.