• Two hundred schizophrenics were compared to 200 normal controls on a measure of laterality that included handedness, footedness, and eye dominance scales. Schizophrenics showed more left-sidedness on the laterality score. The established relationship between motoric and cognitive aspects of functional brain asymmetry, found in neurological and normal populations, suggests that the leftward tendency of schizophrenics may be manifested in cognitive and conative functions as well. These results seem to corroborate previous findings indicating that schizophrenia might be related to left hemisphere dysfunction. No relationship was found between handedness and eye dominance either in the schizophrenic or the normal groups. This finding questions the assumption that eyedness-handedness nonconcordance is a pathological sign.
Gur RE. Motoric Laterality Imbalance in SchizophreniaA Possible Concomitant of Left Hemisphere Dysfunction. Arch Gen Psychiatry. 1977;34(1):33-37. doi:10.1001/archpsyc.1977.01770130035003