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March 1977

Anorexia Nervosa and Gonadal DysgenesisFurther Evidence of a Relationship

Author Affiliations

From the Department of Psychiatry, Albert Einstein College of Medicine, Montefiore Hospital and Medical Center, Bronx, NY.

Arch Gen Psychiatry. 1977;34(3):332-335. doi:10.1001/archpsyc.1977.01770150090010

• We report the ninth documented coincidence of anorexia nervosa and XO gonadal dysgenesis (Turner syndrome) and the second confirmed coincidence of anorexia nervosa and XO/XX (mosaic) gonadal dysgenesis. Three other women who had anorexia nervosa and clinical stigmata of gonadal dysgenesis, but who were not karyotyped, are also described. We thus consider the possibility that patients with gonadal dysgenesis are at special risk for anorexia nervosa and discuss hypotheses to explain such a relationship.