• The possible morbidity suppressive effect of lithium carbonate on cycloid psychosis has been investigated in 30 patients who had suffered from recurrent episodes. The patients were followed up from 1 to 8.5 years after starting lithium treatment. In the analysis, patients were divided into those who took lithium regularly and those who took it irregularly, the division being based on the lithium plasma levels at the periodic control examinations. The study, which is of the so-called mirror type, supports the hypothesis that well-conducted lithium maintenance treatment has a favorable morbidity suppressive effect in patients suffering from cycloid psychosis.
Perris C. Morbidity Suppressive Effect of Lithium Carbonate in Cycloid Psychosis. Arch Gen Psychiatry. 1978;35(3):328-331. doi:10.1001/archpsyc.1978.01770270078007