January 1979

Electroencephalographic Similarities Between Chronic Alcoholics and Chronic, Nonparanoid Schizophrenics

Author Affiliations

From the Research Service, Brentwood Veterans Administration Hospital, Los Angeles, and the Neuropsychiatric Institute, University of California at Los Angeles (Drs Coger and Serafetinides); Pain Center, City of Hope National Medical Center, Duarte, Calif (Dr Coger); and Brain Research Institute, University of California at Los Angeles (Dr Dymond).

Arch Gen Psychiatry. 1979;36(1):91-94. doi:10.1001/archpsyc.1979.01780010097011

• We compared the EEG power spectral density patterns for chronic, nonparanoid schizophrenics and age-matched chronic alcoholic and control subjects. Bilateral precentral (F-T) and postcentral (C-O) derivations were used in the analysis. The nonparanoid schizophrenics and alcoholics showed increased low-frequency activity (O to 6 Hz) in all derivations in comparison to the control subjects. Chronic alcoholics were found to have increased high-frequency activity primarily in the precentral derivations. Nonparanoid schizophrenics showed increased power in the high-frequency bands predominantly in the left precentral derivation. We discuss the implications of patterns of differences concerning the issue of nonspecificity of the EEG in psychiatry.