• To examine the effects of the sex of a psychiatrically disturbed parent on the offspring, we compared children of a schizophrenic parent, a psychiatrically disturbed but not schizophrenic parent, and a normal parent using behavioral, attentional, and neurological indices. Results of a discriminant analysis indicate that children of psychiatrically disturbed mothers have an increased sensitivity to tactile stimulation, possibly reflecting more labile autonomic nervous system functioning. In addition, children with a schizophrenic parent of either sex show evidence of neurological motor dysfunction.
Orvaschel H, Mednick S, Schulsinger F, Rock D. The Children of Psychiatrically Disturbed ParentsDifferences as a Function of the Sex of the Sick Parent. Arch Gen Psychiatry. 1979;36(6):691-695. doi:10.1001/archpsyc.1979.01780060081009