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June 1980

Children at Risk for SchizophreniaClinical and Attentional Characteristics

Author Affiliations

From the Department of Psychiatry, McMaster University School of Medicine, Hamilton (Drs MacCrimmon and Cleghorn); the Hamilton Psychiatric Hospital, Hamilton (Dr MacCrimmon); and the Department of Psychiatry, University of Waterloo, Waterloo (Drs Asarnow and Steffy); Ontario.

Arch Gen Psychiatry. 1980;37(6):671-674. doi:10.1001/archpsyc.1980.01780190069008

• Adolescent high-risk subjects, offspring of schizophrenic mothers, who were placed in foster homes at an early age, are compared with foster children whose biological parents have no record of psychiatric hospitalization and with non-foster children. The high-risk group showed increased social isolation, difficulties in the student role, elevated total symptom scores on the Psychiatric Status Schedule, and elevated schizophrenic scale scores on the Minnesota Multiphasic Personality Inventory. Half of the high-risk subjects showed significant impairment on a battery of eight attention-demanding tasks.