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Article
November 1980

A Blind Family History Study of Briquet's SyndromeFurther Validation of the Diagnosis

Author Affiliations

From the Department of Psychiatry, the University of Iowa College of Medicine, Iowa City.

Arch Gen Psychiatry. 1980;37(11):1266-1269. doi:10.1001/archpsyc.1980.01780240064007
Abstract

• We undertook a blind family history study of Briquet's syndrome to complement earlier follow-up work by Perley and Guze. The same criteria were used in a chart review to select 49 Briquet's syndrome cases. One control group consisted of consecutive "non-Briquet hysteria" admissions and another of matched primary unipolar depressed cases. First-degree relatives of the Briquet's syndrome probands had significantly less affective disorder and more "complicated medical history" then either control group. The "non-Briquet hysteria" group contained more family histories with instances of schizophrenia than either the Briquet's syndrome or affective disorder groups. These results provide additional validation of the Briquet's syndrome diagnosis.

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