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April 1981

Treatment of Traumatic War Neurosis With Phenelzine

Author Affiliations

From the Department of Psychiatry, Bronx VA Medical Center, and the Mount Sinai School of Medicine, City University of New York, New York. Dr Cornfield is now with the Philadelphia VA Ambulatory Care Center and the University of Pennsylvania School of Medicine, Philadelphia.

Arch Gen Psychiatry. 1981;38(4):440-445. doi:10.1001/archpsyc.1981.01780290074008

• Traumatic war neurosis may become a chronic, debilitating condition that resists treatment interventions. Five patients with traumatic war neurosis had favorable therapeutic responses to phenelzine sulfate. These patients did not respond to multiple previous therapeutic trials with antipsychotics, tricyclic antidepressants, and psychotherapy with or without medication. With phenelzine, the patients felt calmer and stopped having nightmares and flashbacks of traumatic war material. Startle reactions and aggressive, violent outbursts also ceased.