October 1982

Primary Unipolar Depression and the Prognostic Importance of Delusions

Author Affiliations

From the Department of Psychiatry, University of Iowa, Iowa City. Dr Tsuang is now with the Section of Psychiatry and Human Behavior, Brown University, and Psychiatric Epidemiology Research Unit, Butler Hospital, Providence, RI.

Arch Gen Psychiatry. 1982;39(10):1181-1184. doi:10.1001/archpsyc.1982.04290100051008

• A consecutive series of inpatients with primary unipolar depression was categorized by the presence or absence of delusions as noted in the charts. The systematically obtained follow-up material contained in these charts showed that delusional patients had a relatively poor short-term outcome regardless of whether they received somatic treatment.Recovery rate increased with longer follow-up periods in both groups. In accord with this, a 40-year follow-up revealed no differences between delusional and nondelusional groups in terms of marital, residential, or occupational status, psychiatric symptoms, a final diagnosis of bipolar disorder, or death by suicide.