• High prostaglandin E2 concentrations were found in the CSF of women with unipolar depression and character disorder. This finding seemed to be relatively specific; it was not observed in bipolar depressed and psychotic schizophrenic patients.
Linnoila M, Whorton AR, Rubinow DR, Cowdry RW, Ninan PT, Waters RN. CSF Prostaglandin Levels in Depressed and Schizophrenic Patients. Arch Gen Psychiatry. 1983;40(4):405-406. doi:10.1001/archpsyc.1983.01790040059008