To the Editor.—
In his article "Sex Difference in Age at Onset of Schizophrenia,"1 Loranger presented data on 100 male and 100 female subjects from a review of medical records. Loranger claimed that these patients unequivocally met the DSM-III criteria for schizophrenia. His cumulative percentage table for the age at onset of schizophrenia showed that 8% of the female subjects had their first psychotic episode at the age of 45 years or older, that 6% of the women were untreated, and that 9% were not hospitalized until the age of 45 years or older. The DSM-III criteria specify the onset of the prodromal or active phase of illness before the age of 45 years for a diagnosis of schizophrenia. This definition calls into doubt the consideration of female patients older than 45 years who were included in this report as unequivocally schizophrenic.
Orlosky MJ. Schizophrenia and Age Considerations. Arch Gen Psychiatry. 1984;41(8):819. doi:10.1001/archpsyc.1984.01790190093014