• The electroencephalographic sleep of younger depressives (aged 20 to 44 years) was compared with that of an age-matched group of normals. The patients demonstrated many of the typical sleep changes reported for older depressed populations: shortened rapid-eye-movement (REM) latency; REM sleep activity alterations, with a shift to the early portion of the night (first REM period); reduced delta sleep; and sleep efficiency reductions marked by sleep-onset difficulties. The traditional scoring procedures were supplemented by automated REM and delta-sleep analyses that provided more precise delineation of these differences between patients and normals, particularly the distributions of REM activity and delta-wave patterning.
Kupfer DJ, Ulrich RF, Coble PA, Jarrett DB, Grochocinski VJ, Doman J, Matthews G, Borbély AA. Electroencephalographic Sleep of Younger DepressivesComparison With Normals. Arch Gen Psychiatry. 1985;42(8):806-810. doi:10.1001/archpsyc.1985.01790310068009