• Fifty-seven patients with situational major depression diagnosed by the Research Diagnostic Criteria were compared with 72 subjects with nonsituational major depression on demographic, clinical, and psychosocial variables. The situational patients tended to be younger and had fewer prior episodes of depression and fewer hospitalizations. No differences were found in categories of life events, in overall clinical picture, in social supports, or in family history.
Hirschfeld RMA, Klerman GL, Andreasen NC, Clayton PJ, Keller MB. Situational Major Depressive Disorder. Arch Gen Psychiatry. 1985;42(11):1109-1114. doi:10.1001/archpsyc.1985.01790340093013