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January 1992

Subjective Conclusions About Schizophrenia-Reply

Author Affiliations

Department of Psychiatry Maryland Psychiatric Research Center University of Maryland School of Medicine PO Box 21247 Baltimore, MD 21228
Bethesda, Md
Pittsburgh, Pa

Arch Gen Psychiatry. 1992;49(1):74-75. doi:10.1001/archpsyc.1992.01820010074010

In Reply.—  We appreciate Puryear and colleagues' interest in our recent article.1 They apparently do not find fault with the methods used Or data contained in our report. Rather, they believe our interpretations of the data were inaccurate, which, they suggest, may lead to "unduly pessimistic" conclusions about the long-term outcome of schizophrenia. They specifically point to our phasic model of course of illness, indicating that the figure reflects a more negative course than does our discussion of themodel.Our phasic model represents a synthesis of several previously published outcome studies. There were vast differences in the methods used in these studies, so it was impossible to use a single outcome measure, such as Global Assessment Scale or Levels ofFunctioning scores, to synthesize the data. Thus, we believe it would have been misleading to "score" the y axis in our figure. Our phasic model was developed as an attempt to

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