July 1992

Psychosurgical Treatment of Obsessivecompulsive Disorder

Author Affiliations

Neuropsychiatric Institute The Prince Henry Hospital Sydney, Australia

Arch Gen Psychiatry. 1992;49(7):582-583. doi:10.1001/archpsyc.1992.01820070076014

To the Editor. —  The article by Jenike et al1 in the June 1991 issue of the Archives is of great interest, as it provides sound empirical data in an area where many scientific, ethical, and social issues remain unresolved.We recently completed a longitudinal study of 26 patients with medically intractable obsessive-compulsive disorder (OCD) who were treated with psychosurgery at our unit during the past two decades.2 In the light of similarities of intention and design between the two studies, a comparison of the results and their interpretation is noteworthy.

Subjects and Methods.—  The records of patients who had undergone psychosurgery revealed that six (23%) of our 26 patients had cingulate lesions only, three (12%) had bilateral orbitomedial lesions, and 17 (65%) had "combined" cingulate and orbitomedial lesions. Six patients (before 1974) underwent open leukotomy and 20 underwent stereotactic surgery. Three patients were dead at follow-up (two

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