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October 1, 2012, Vol 69, No. 10, Pages 990-1086

This Month in Archives of General Psychiatry

This Month in Archives of General Psychiatry

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Arch Gen Psychiatry. 2012;69(10):991-991. doi:10.1001/archgenpsychiatry.2011.1229
Art and Images in Psychiatry

Olive Trees in a Mountainous Landscape

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Arch Gen Psychiatry. 2012;69(10):992-992. doi:10.1001/archgenpsychiatry.2012.109
Original Article

Serotonin and the Neural Processing of Facial Emotions in Adults With AutismAn fMRI Study Using Acute Tryptophan Depletion

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Arch Gen Psychiatry. 2012;69(10):1003-1013. doi:10.1001/archgenpsychiatry.2012.513

Daly and colleagues conducted a double-blind, placebo-controlled crossover trial of acute tryptophan depletion and functional magnetic resonance imaging to compare the effects of acute tryptophan depletion on brain responses to primary facial expressions of emotion in men with autism spectrum disorders and healthy control subjects.

Guilt-Selective Functional Disconnection of Anterior Temporal and Subgenual Cortices in Major Depressive Disorder

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Arch Gen Psychiatry. 2012;69(10):1014-1021. doi:10.1001/archgenpsychiatry.2012.135

In a prospective study, Green and coauthors investigated guilt-selective decoupling between the subgenual cingulate cortex and adjacent septal region and the anterior temporal lobe in patients with remitted major depressive disorder compared with healthy control participants.

Alterations in Neural Processing and Psychopathology in Children Raised in Institutions

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Arch Gen Psychiatry. 2012;69(10):1022-1030. doi:10.1001/archgenpsychiatry.2012.444

Slopen and colleagues drew data from the Bucharest Early Intervention Project, a cohort of children raised in institutions in Romania and an age-matched sample of community control subjects. The aim was to examine whether abnormalities in the neural processing of facial and emotional stimuli are related to the high rates of psychopathology observed among institutionally reared children.

Prevalence and Persistence of Psychiatric Disorders in Youth After DetentionA Prospective Longitudinal Study

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Arch Gen Psychiatry. 2012;69(10):1031-1043. doi:10.1001/archgenpsychiatry.2011.2062

In a prospective study, Teplin and coauthors examine changes in the prevalence and persistence of psychiatric disorders during the 5 years after detention of 1829 youths, focusing on sex and racial/ethnic differences.

Dopaminergic Mechanisms of Reduced Basal Ganglia Responses to Hedonic Reward During Interferon Alfa Administration

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Arch Gen Psychiatry. 2012;69(10):1044-1053. doi:10.1001/archgenpsychiatry.2011.2094

To determine whether long-term interferon alfa administration reduces the basal ganglia response to reward and whether such changes are associated with decreased presynaptic striatal dopamine function and altered behavior, Capuron and coauthors studied medically stable adults with chronic hepatitis C virus infection.

The Associations of Insomnia With Costly Workplace Accidents and ErrorsResults From the America Insomnia Survey

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Arch Gen Psychiatry. 2012;69(10):1054-1063. doi:10.1001/archgenpsychiatry.2011.2188

Insomnia has been implicated in impaired workplace functioning, but employers have not invested in workplace screening and treatment. Shahly et al estimated the prevalence and costs to employers of insomnia-related accidents and/or errors and made annualized national projections to the entire US workforce.

Functional Brain Basis of Hypnotizability

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Arch Gen Psychiatry. 2012;69(10):1064-1072. doi:10.1001/archgenpsychiatry.2011.2190

Focused hypnotic concentration is a model for brain control over sensation and behavior. Pain and anxiety can be effectively alleviated by hypnotic suggestion, which modulates activity in brain regions associated with focused attention. Hoeft and associates investigate the brain basis of hypnotizability.

Twenty-Year Depressive Trajectories Among Older Women

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Arch Gen Psychiatry. 2012;69(10):1073-1079. doi:10.1001/archgenpsychiatry.2012.43

Byers et al used latent class growth curve analysis to characterize the natural course of depressive symptoms among 7240 community-dwelling women 65 years or older who were enrolled at 4 clinic sites in an ongoing prospective cohort study and were followed up for almost 20 years. The Geriatric Depression Scale short form (GDS) was routinely administered.

Amygdala Volume in Combat-Exposed Veterans With and Without Posttraumatic Stress DisorderA Cross-sectional Study

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Arch Gen Psychiatry. 2012;69(10):1080-1086. doi:10.1001/archgenpsychiatry.2012.73

Kuo et al compare amygdala volumes between 99 combat veterans with and without PTSD and examine the effect of trauma exposure in childhood and the severity of combat exposure in adulthood.

Alterations in Default Mode Network Connectivity During Pain Processing in Borderline Personality Disorder

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Arch Gen Psychiatry. 2012;69(10):993-1002. doi:10.1001/archgenpsychiatry.2012.476

Kluetsch et al connect the previously separate research areas of default mode network connectivity and altered pain perception in borderline personality disorder (BPD) and explore default mode network connectivity during pain processing in patients with BPD.

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