Schellekens and coauthors conducted a case-control pharmacogenetic challenge study to test central dopamine receptor sensitivity as an intermediate phenotype for alcohol dependence.
Whether patients with schizophrenia and patients with bipolar disorder display overlapping abnormalities in brain volumes and cortical thickness and whether these are caused by shared genetic or environmental influences were investigated by Hulshoff Pol et al.
Aupperle and coauthors conducted a case-control, cross-sectional study to determine whether posttraumatic stress disorder (PTSD) relates to greater disruption in prefrontal-subcortical networks during emotional anticipation.
Kessler et al present estimates of 12-month and 30-day prevalence, persistence (12-month prevalence among lifetime cases and 30-day prevalence among 12-month cases), and sociodemographic correlates of commonly occurring DSM-IV disorders among adolescents in the National Comorbidity Survey Replication Adolescent Supplement (NCS-A).
Kessler et al present national data on the 12-month prevalence and sociodemographic correlates of serious emotional disturbances.
Swendsen et al examine the prevalence, age at onset, and sociodemographic correlates of alcohol and illicit drug use and abuse among US adolescents.
In a cross-sectional case-control study comparing serotonin2A receptor levels in abstinent female MDMA (3,4-methylenedioxymethamphetamine) polydrug users with those in women who did not use MDMA, Di Iorio and coauthors determine whether MDMA use is associated with chronic reductions in serotonin signaling in the cerebral cortex of women as reflected by increased serotonin2A receptor levels.
Katon et al determine whether comorbid depression in patients with type 2 diabetes increases the risk of development of dementia.
The availability of nicotinic acetylcholine receptors containing the β2 subunit (β2*-nAChRs) in male and female smokers vs nonsmokers was studied by Cosgrove et al and the associations among nicotinic acetylcholine receptors containing the β2 subunit availability, tobacco smoking characteristics, and female sex steroid hormone levels was determined.
Using a population-based cohort, Munk-Olsen et al study to what extent psychiatric disorders with postpartum onset are early manifestations of an underlying bipolar affective disorder.